Participants needed for Parkinson’s study

Parkinson's is a progressive neurological condition. It causes problems in the brain and gets worse over time. The number of people diagnosed with Parkinson's in the UK is about 145,000. This equates to around 1 adult in every 350.

Participants needed for Parkinson’s study

Cornwall’s NHS is calling for those living with Parkinson’s disease to take part in a research study to trial a new type of medication for dyskinesia.

Dyskinesia is when a person with Parkinson’s makes involuntary movement caused by their Parkinson’s medication. Movements can include twitches, jerks, twisting and writhing movements, as well as restlessness.

The three main symptoms of Parkinson’s are tremor, stiffness and slowness of movement. Some may experience problems with sleep, memory and mental health issues. Symptoms start to appear when the brain can’t make enough dopamine to control movement properly.

The study will trial the effectiveness of a new oral medication which aims to improve symptoms of dyskinesia. Currently the medication is not yet available to those living with the disease.

Lynne Osborne, who is Cornwall Partnership NHS Foundation Trust’s Nurse Consultant for the Parkinson’s Service is the Principal Investigator for this clinical trial. Lynne will be working with the Trust’s Research Team to look into the effectiveness of the trial medication.

Lynne commented, “This is an exciting research study to be taking part in. The trial medication could significantly reduce involuntary movement caused by Parkinson’s medication. Many find this symptom to be extremely disabling.”

If you are aged 79 or younger, have Parkinson’s and are experiencing symptoms of dyskinesia for at least 25% of your day, you could be eligible to take part in the trial.

The trial will take place over four weeks at Royal Cornwall Hospital Trust Treliske’s Knowledge Spa in Truro and you will either be allocated the trial drug or a placebo, in addition to your regular Parkinson’s medication.

To find out if you are suitable to take part in the study, please telephone the Trust’s Research Team on 01209204020 or email cpn-trCFTResearch@nhs.net. Those taking part in the study will have their travel expenses reimbursed.

If you would like to know more about other research studies taking place please visit https://www.parkinsons.org.uk/get-involved